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Education
Pediatric Infectious Diseases Fellowship
2017
Clinical Investigation Sciences Master's Degree
2017
Biological Sciences Bachelor's of Science Degree with Honors (Minor in Chemistry)
2006
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Certifications
Pediatric Infectious Diseases
2017
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Professional Leadership
Vice Chair for Education
2018 - Present
Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic
Associate Professor of Pediatrics
2024 - Present
Mayo Clinic College of Medicine and Science
Electronic Medical Record (EMR) Director
2020 - Present
Mayo Clinic Children's CenterPrimary Superuser for the Children Center
Associate Program Director
2020 - 2025
Pediatric and Adolescent Residency Program, Mayo Graduate School of Medicine, Mayo Clinic College of Medicine and Science
Program Director
2020 - Present
Fellowship, Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine
Consultant
2020 - Present
Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota
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Selected Publications
A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics
2025
A newly discovered dominant-negative IRF8 mutation identified in a mother and son impairs dendritic cell function and broadens the clinical phenotype associated with IRF8-related immunodeficiency.
Mittens and Booties Syndrome: A Unique Manifestation of Human Parechovirus Infection in Infants
2019
We describe the first 2 cases from the United States, of human parechovirus infection in infants manifesting a distinct rash of the hands and feet. We propose the term "Mittens and Booties Syndrome" and provide a review of the literature of all published cases.
Effect of Intranasal Mupirocin Prophylaxis on Methicillin-Resistant Staphylococcus aureus Transmission and Invasive Staphylococcal Infections in a Neonatal Intensive Care Unit
2018
The use of monthly intranasal mupirocin was associated with a significant reduction in the rate of methicillin-resistant Staphylococcus aureus transmission and Staphylococcus aureus invasive infection in a large neonatal intensive care unit. Resistance to mupirocin emerged over time, but it was rare and was not associated with adverse clinical outcomes.
The Mask
2013
The personal experience of a medical trainee with their patient's death and funeral.
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About Me

Dr. Ristagno is from Cincinnati, Ohio and graduated from the University of Cincinnati with a bachelor’s degree in biology. She then earned her Medical Degree from the University of Louisville School of Medicine. She remained in Louisville Kentucky for her pediatric residency at Kosair Children’s Hospital, board certified by the American Academy of Pediatrics since 2014. She then completed a pediatric infectious diseases fellowship and simultaneously a Masters in Clinical Investigative Sciences. After graduation, she was hired by Mayo Clinic.

Dr. Ristagno has a special clinical interest in bacterial infections and primary immunodeficiency; she also has an interest in medical education and serves as the program director for Mayo Clinic’s pediatric infectious diseases fellowship.

She lives in Rochester, Minnesota with her husband and goldendoodle, Figment. She enjoys playing violin and viola. She also enjoys crafts, Harry Potter (self-proclaimed Ravenclaw), Disney World, ancient Roman history, and is a Latin language enthusiast.